Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.31 |
| ▸ | CCR2 | P41597 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701430 | 0.90 | CA1 (0.33) | MAOBLMNANPC1GAAMAPT | |
| SCHEMBL9701113 | 0.88 | MAOB (0.31) | MAOBABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9701174 | 0.84 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9535908 | 0.81 | CHRNB2 (0.34) | KMT2AMAPK1L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL9436772 | 0.81 | CHRNB2 (0.34) | KMT2AMAPK1L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL9702143 | 0.79 | MAOB (0.32) | MAOBKDM4E | |
| SCHEMBL9702535 | 0.72 | MAPT (0.35) | KDM4ELMNAALDH1A1GAAMAPT | |
| SCHEMBL7902272 | 0.71 | KDM4E (0.32) | KDM4EALDH1A1POLB | |
| SCHEMBL9701097 | 0.70 | SIGMAR1 (0.34) | MAOBSLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL9702241 | 0.69 | RAB9A (0.33) | KDM4ELMNAKMT2AALDH1A1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013860-A1 | NEW 4,5,6,7-TETRAHYDRO-IMIDAZO-[4,5,lJK][1,4]-BENZODIAZEPINE-2-(1H)-THIONES, A METHOD OF PREPARING THEM AS WELL AS DRUGS CONTAINING THEM, AND INTERMEDIATES FOR THE PREPARATION OF THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-20 | — | — | WO | disclosed |