Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702143 | 0.91 | MAOB (0.32) | MAOB | |
| SCHEMBL9700197 | 0.88 | MAOB (0.32) | MAOBABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9701430 | 0.78 | CA1 (0.33) | MAOB | |
| SCHEMBL9701174 | 0.75 | SLC6A2 (0.36) | — | |
| SCHEMBL9702543 | 0.69 | — | — | |
| SCHEMBL7902272 | 0.68 | KDM4E (0.32) | — | |
| SCHEMBL9535908 | 0.68 | CHRNB2 (0.34) | — | |
| SCHEMBL7908084 | 0.62 | HRH4 (0.35) | — | |
| SCHEMBL9701097 | 0.61 | SIGMAR1 (0.34) | MAOB | |
| SCHEMBL768764 | 0.60 | ALDH1A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013860-A1 | NEW 4,5,6,7-TETRAHYDRO-IMIDAZO-[4,5,lJK][1,4]-BENZODIAZEPINE-2-(1H)-THIONES, A METHOD OF PREPARING THEM AS WELL AS DRUGS CONTAINING THEM, AND INTERMEDIATES FOR THE PREPARATION OF THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-20 | — | — | WO | disclosed |