Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655423 | 0.90 | ALDH1A1 (0.59) | ALDH1A1GAAPAOXLMNAKMT2A | |
| SCHEMBL9701323 | 0.88 | SIGMAR1 (0.46) | ALDH1A1LMNAKMT2ACYP2D6KDM4E | |
| Hydrochloric Acid SCHEMBL9701581 | 0.86 | LMNA (0.47) | ALDH1A1LMNAKMT2ACYP2D6KDM4E | |
| SCHEMBL17415969 | 0.83 | ALDH1A1 (0.62) | ALDH1A1GAAPAOXLMNAKMT2A | |
| SCHEMBL29511205 | 0.82 | ALDH1A1 (0.53) | ALDH1A1GAAPAOXLMNAKMT2A | |
| SCHEMBL8854209 | 0.82 | ALDH1A1 (0.53) | ALDH1A1GAAPAOXLMNAKMT2A | |
| SCHEMBL7260964 | 0.81 | ALDH1A1 (0.59) | ALDH1A1GAAPAOXLMNAKMT2A | |
| SCHEMBL93199 | 0.81 | ALDH1A1 (0.51) | ALDH1A1GAAPAOXLMNAKMT2A | |
| SCHEMBL15830183 | 0.79 | ALDH1A1 (0.50) | ALDH1A1GAAPAOXLMNAKMT2A | |
| SCHEMBL8854211 | 0.79 | ALDH1A1 (0.50) | ALDH1A1GAAPAOXLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132454-A | Antihypoxic agents | MEIJI SEIKA KAISHA, LTD. (JP) | 1992-07-21 | — | — | US | disclosed |
| US-5066677-A | Antihypoxic agents, treatment of disorders resulting from reduced oxygen supply to brain | MEIJI SEIKA KAISHA, LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0387074-A2 | Novel oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain | MEIJI SEIKA KAISHA LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |