Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9701581 | 0.98 | LMNA (0.47) | SIGMAR1ALDH1A1LMNAACHEKMT2A | |
| SCHEMBL13655355 | 0.89 | ALDH1A1 (0.53) | SIGMAR1ALDH1A1LMNAACHEKMT2A | |
| SCHEMBL9700334 | 0.88 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2AKDM4ECYP2D6 | |
| Methacrylic Acid SCHEMBL8762478 | 0.83 | ALDH1A1 (0.43) | SIGMAR1ALDH1A1LMNAACHEKMT2A | |
| SCHEMBL2835194 | 0.82 | ALDH1A1 (0.49) | SIGMAR1ALDH1A1LMNAACHEKMT2A | |
| SCHEMBL7241259 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAACHEKMT2ASLC22A2 | |
| SCHEMBL3634362 | 0.81 | ALDH1A1 (0.49) | SIGMAR1ALDH1A1LMNAACHEKMT2A | |
| Acetic Acid SCHEMBL8192294 | 0.80 | ALDH1A1 (0.44) | SIGMAR1ALDH1A1LMNAACHEKMT2A | |
| SCHEMBL4940443 | 0.79 | KMT2A (0.59) | ALDH1A1LMNAACHEKMT2ASLC22A2 | |
| SCHEMBL93180 | 0.79 | ALDH1A1 (0.47) | SIGMAR1ALDH1A1LMNAACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132454-A | Antihypoxic agents | MEIJI SEIKA KAISHA, LTD. (JP) | 1992-07-21 | — | — | US | disclosed |
| US-5066677-A | Antihypoxic agents, treatment of disorders resulting from reduced oxygen supply to brain | MEIJI SEIKA KAISHA, LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0387074-A2 | Novel oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain | MEIJI SEIKA KAISHA LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |