SCHEMBL9700470

SCHEMBL9700470

CN1CCNc2cc([N+](=O)[O-])ccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.48
GAA P10253 4/20 0.48
L3MBTL1 Q9Y468 1/20 0.44
LMNA P02545 6/20 0.44
NPC1 O15118 1/20 0.43
MAPT P10636 1/20 0.43
RAB9A P51151 1/20 0.43
CASP1 P29466 1/20 0.43
CASP3 P42574 1/20 0.43
CASP4 P49662 1/20 0.43
CASP7 P55210 1/20 0.43
CASP9 P55211 1/20 0.43
CASP6 P55212 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
KMT2A Q03164 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30026696 1.00 ALDH1A1 (0.48) ALDH1A1GAAL3MBTL1LMNANPC1
SCHEMBL2061806 0.81 CASP3 (0.43) ALDH1A1GAANPC1MAPTRAB9A
SCHEMBL2060905 0.81 CASP3 (0.50) ALDH1A1GAALMNAMAPTCASP1
SCHEMBL2061012 0.78 TDP1 (0.45) ALDH1A1GAAL3MBTL1LMNAMAPT
SCHEMBL9499652 0.77 L3MBTL1 (0.51) ALDH1A1GAAL3MBTL1LMNACASP1
SCHEMBL27490442 0.77 PNMT (0.56) ALDH1A1GAALMNACASP1CASP3
Hydrochloric Acid SCHEMBL7552765 0.75 PNMT (0.55) ALDH1A1GAALMNACASP1CASP3
SCHEMBL23769053 0.75 ALDH1A1 (0.50) ALDH1A1GAAL3MBTL1LMNANPC1
SCHEMBL13217272 0.74 ALDH1A1 (0.48) ALDH1A1GAALMNAMAPTSMN1; SMN2
SCHEMBL24316839 0.74 PNMT (0.39) ALDH1A1SMN1; SMN2NR1H2NR1H3HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5089025-A HAIR DYE COMPOSITIONS AND CERTAIN 1,2,3,4-TETRAHYDRONITROQUINOXALINES USEFUL THEREIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1992-02-18 US disclosed