Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3878183 | 0.84 | TUBB4A (0.50) | TAS2R14NPSR1PDE4BACLYLMNA | |
| SCHEMBL26732612 | 0.84 | TAS2R14 (0.40) | TAS2R14KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL167782 | 0.83 | KDM4E (0.47) | TAS2R14KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4480620 | 0.82 | TAS2R14 (0.46) | TAS2R14KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL15880328 | 0.81 | KDM4E (0.46) | TAS2R14KDM4EALDH1A1HPGDHSD17B10 | |
| Nitrous Acid SCHEMBL27942685 | 0.81 | TAS2R14 (0.43) | TAS2R14KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24868103 | 0.81 | TAS2R14 (0.45) | TAS2R14KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30546054 | 0.81 | TAS2R14 (0.39) | TAS2R14KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL22235111 | 0.81 | LMNA (0.39) | TAS2R14ALDH1A1MAPTPDE4BLMNA | |
| SCHEMBL6376901 | 0.81 | TAS2R14 (0.45) | TAS2R14KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166060-A | Prepared by the action of 2,3-dihydroxybenzoate-3,4-dioxygenase on 2,3-dihydroxybenzoic acid | CELGENE CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| EP-0390102-A2 | Process for the preparation of pyridine-2,3-dicarboxylic acids | CELGENE CORPORATION (US) | 1990-10-03 | — | — | EP | disclosed |
| US-4923504-A | 2-(2-Imidazolin-2-yl)pyridines and quinolines, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4798619-A | 2-(2-imidazolin-2-yl)-pyridines and quinolines and use of said compounds as herbicidal agents | AMERICAN CYANAMID CO. (US) | 1989-01-17 | — | — | US | disclosed |
| US-4638068-A | 2-(2-imidazolin-2-yl)-pyridines and quinolines, process and intermediates for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1987-01-20 | — | — | US | disclosed |