Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | XPO1 | O14980 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5262306 | 0.87 | TUBB4A (0.50) | TAS2R14LMNANPC1RAB9AKDM4E | |
| SCHEMBL4188205 | 0.85 | LMNA (0.46) | LMNANPC1RAB9AGAAP2RX7 | |
| SCHEMBL4480620 | 0.82 | TAS2R14 (0.46) | TAS2R14LMNANPC1RAB9AKDM4E | |
| SCHEMBL24868103 | 0.81 | TAS2R14 (0.45) | TAS2R14LMNANPC1RAB9AKDM4E | |
| SCHEMBL9700547 | 0.81 | TAS2R14 (0.45) | TAS2R14LMNANPC1RAB9AKDM4E | |
| SCHEMBL21645056 | 0.81 | ALDH1A1 (0.41) | TAS2R14KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL122983 | 0.80 | TAS2R14 (0.40) | TAS2R14LMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL165279 | 0.79 | KEAP1 (0.46) | TAS2R14LMNANPC1RAB9AKDM4E | |
| SCHEMBL167782 | 0.79 | KDM4E (0.47) | TAS2R14LMNANPC1RAB9AKDM4E | |
| SCHEMBL1267198 | 0.79 | XPO1 (0.56) | KDM4EHPGDALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020016345-A1 | Pyridine ketones useful as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2002-02-07 | — | — | US | claimed |
| EP-1114030-A1 | PYRIDINE KETONES USEFUL AS HERBICIDES | Syngenta Participations AG (CH) | 2001-07-11 | — | — | EP | claimed |
| WO-2000015615-A1 | PYRIDINE KETONES USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-03-23 | — | — | WO | claimed |
| US-4747871-A | 2,6-bis(trifluoromethyl)-3-hydroxycarbonyl pyridine, salts and gametocides | MONSANTO COMPANY (US) | 1988-05-31 | — | — | US | claimed |
| US-20090137558-A1 | Pyridine based compounds useful as intermediates for pharmaceutical or agricultural end-products | PEAKDALE MOLECULAR LIMITED (GB) | 2009-05-28 | — | — | US | disclosed |
| US-20090137558-A1 | Pyridine based compounds useful as intermediates for pharmaceutical or agricultural end-products | PEAKDALE MOLECULAR LIMITED (GB) | 2009-05-28 | — | — | US | disclosed |
| EP-1114030-B1 | PYRIDINE KETONES USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-01 | — | — | EP | disclosed |
| US-6358634-B1 | LIGHT EMITTING DIODES WITH ORGANOMETALLIC COMPLEXES | FUJI PHOTO FILM CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1114030-A1 | PYRIDINE KETONES USEFUL AS HERBICIDES | Syngenta Participations AG (CH) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000015615-A1 | PYRIDINE KETONES USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-03-23 | — | — | WO | disclosed |
| US-4747871-A | 2,6-bis(trifluoromethyl)-3-hydroxycarbonyl pyridine, salts and gametocides | MONSANTO COMPANY (US) | 1988-05-31 | — | — | US | disclosed |
| US-4747871-A | 2,6-bis(trifluoromethyl)-3-hydroxycarbonyl pyridine, salts and gametocides | MONSANTO COMPANY (US) | 1988-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016345-A1 | Pyridine ketones useful as herbicides | DDT, PDHA1, IDH2 | TAS2R14 2962/4885LMNA 4284/4885NPC1 4388/4885 |
| US-20090137558-A1 | Pyridine based compounds useful as intermediates for pharmaceutical or agricultural end-products | PNPO, CYP4B1, PDXK | TAS2R14 4506/4885LMNA 3915/4885NPC1 3973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.