Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500774 | 0.85 | IDO1 (0.41) | HTR1ASLC6A4ADRA1ATAAR1HTR2A | |
| SCHEMBL7551792 | 0.84 | ADRA1A (0.48) | HTR1ASLC6A4ADRA1ATAAR1HTR2A | |
| SCHEMBL10053221 | 0.81 | L3MBTL1 (0.37) | HTR1ASLC6A4TAAR1HTR2A | |
| SCHEMBL7478730 | 0.80 | NOS3 (0.38) | HTR1ASLC6A4HTR2AIDO1 | |
| SCHEMBL500012 | 0.80 | HTR2A (0.36) | HTR1ASLC6A4HTR2AHTR2C | |
| SCHEMBL17330013 | 0.79 | HTR1A (0.45) | HTR1ASLC6A4ADRA1ATAAR1HTR2A | |
| SCHEMBL15376943 | 0.79 | HTR1A (0.45) | HTR1ASLC6A4ADRA1ATAAR1HTR2A | |
| SCHEMBL989673 | 0.77 | TAAR1 (0.66) | HTR1ASLC6A4ADRA1ATAAR1HTR2A | |
| SCHEMBL12428735 | 0.77 | HTR1A (0.44) | HTR1ASLC6A4ADRA1ATAAR1HTR2A | |
| SCHEMBL6401187 | 0.77 | CYP2D6 (0.51) | HTR1ASLC6A4ADRA1ATAAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496548-A1 | Carbacyclin analogs | PURDUE RESEARCH FOUNDATION (US) | 1992-07-29 | — | — | EP | disclosed |