Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700635 | 0.89 | GAA (0.39) | ALDH1A1GAAKDM4EGLAL3MBTL1 | |
| SCHEMBL9528770 | 0.87 | KDM4E (0.48) | ALDH1A1GAAKDM4EGLAL3MBTL1 | |
| SCHEMBL9526113 | 0.85 | MAPT (0.41) | ALDH1A1GAAKDM4EGLAL3MBTL1 | |
| SCHEMBL9701382 | 0.85 | SMN1; SMN2 (0.42) | ALDH1A1GAAKDM4EGLAL3MBTL1 | |
| SCHEMBL9525824 | 0.82 | NPC1 (0.38) | ALDH1A1GAAKDM4EGLAL3MBTL1 | |
| SCHEMBL9700824 | 0.82 | CDC7 (0.45) | ALDH1A1KDM4E | |
| SCHEMBL9701671 | 0.81 | BRD4 (0.42) | ALDH1A1GAAKDM4EGLALMNA | |
| SCHEMBL9700756 | 0.81 | SNCA (0.37) | ALDH1A1GAAKDM4EGLAL3MBTL1 | |
| SCHEMBL9700701 | 0.81 | NOTUM (0.41) | ALDH1A1GAAKDM4EGLAL3MBTL1 | |
| SCHEMBL9700407 | 0.81 | IDO1 (0.41) | ALDH1A1GAAKDM4EGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |