Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528770 | 0.83 | KDM4E (0.48) | NOTUMFGFR1ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL9700756 | 0.81 | SNCA (0.37) | ALDH1A1L3MBTL1KDM4EGLAGAA | |
| SCHEMBL9701671 | 0.81 | BRD4 (0.42) | NOTUMIDO1ALDH1A1KDM4EGLA | |
| SCHEMBL9526113 | 0.81 | MAPT (0.41) | ALDH1A1L3MBTL1KDM4EGLAGAA | |
| SCHEMBL9700666 | 0.81 | ALDH1A1 (0.53) | NOTUMALDH1A1L3MBTL1KDM4EGLA | |
| SCHEMBL9700407 | 0.81 | IDO1 (0.41) | NOTUMIDO1ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL9701382 | 0.80 | SMN1; SMN2 (0.42) | ALDH1A1L3MBTL1KDM4EGLAGAA | |
| SCHEMBL9700824 | 0.80 | CDC7 (0.45) | ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL9702585 | 0.79 | CYP3A4 (0.48) | ALDH1A1KDM4EGAANPC1LMNA | |
| SCHEMBL9700772 | 0.79 | XDH (0.35) | ALDH1A1KDM4EGAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |