Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700679 | 0.87 | MAOA (0.37) | GCKKDM4EMAPTRAB9AL3MBTL1 | |
| SCHEMBL9700772 | 0.84 | XDH (0.35) | GCKKDM4EALDH1A1GAALMNA | |
| SCHEMBL9701671 | 0.81 | BRD4 (0.42) | IDO1KDM4EALDH1A1GAALMNA | |
| SCHEMBL9700756 | 0.81 | SNCA (0.37) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL9700666 | 0.81 | ALDH1A1 (0.53) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL9700701 | 0.81 | NOTUM (0.41) | IDO1KDM4EALDH1A1GAALMNA | |
| SCHEMBL8007196 | 0.79 | IDO1 (0.46) | IDO1LMNAMAPTSMN1; SMN2ALOX5 | |
| SCHEMBL9528770 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1GAAUSP2LMNA | |
| SCHEMBL9251638 | 0.77 | PTGER3 (0.46) | PTGER3 | |
| SCHEMBL9526113 | 0.77 | MAPT (0.41) | KDM4EALDH1A1GAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |