Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.41 |
| ▸ | DPYD | Q12882 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528770 | 0.86 | KDM4E (0.48) | ALDH1A1HPGDKDM4EMAPTTDP1 | |
| SCHEMBL9526113 | 0.84 | MAPT (0.41) | NPSR1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL9525824 | 0.83 | NPC1 (0.38) | ALDH1A1KMT2AKDM4EMAPTTDP1 | |
| SCHEMBL9701382 | 0.83 | SMN1; SMN2 (0.42) | ALDH1A1KMT2ADHODHKDM4EMAPT | |
| SCHEMBL9700666 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4E | |
| SCHEMBL704303 | 0.82 | MAOB (0.51) | NPSR1ALDH1A1HPGDDHODHMAOB | |
| SCHEMBL9700701 | 0.80 | NOTUM (0.41) | ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL1250174 | 0.77 | GSTP1 (0.48) | ALDH1A1HPGDKMT2ADHODHMAOB | |
| SCHEMBL9700679 | 0.77 | MAOA (0.37) | KMT2AMAOBMAOAKDM4EMAPT | |
| SCHEMBL9251638 | 0.76 | PTGER3 (0.46) | GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |