Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700651 | 0.91 | MAPT (0.35) | RAB9ANPC1TP53GAAHSD17B10 | |
| SCHEMBL9526113 | 0.90 | MAPT (0.41) | CYP1A2GAAMAPTLMNATSHR | |
| SCHEMBL9701474 | 0.90 | CYP1A2 (0.41) | RAB9ANPC1TP53CYP1A2GAA | |
| SCHEMBL9701708 | 0.88 | PDE3B (0.33) | CYP1A2GAAHSD17B10MAPTALDH1A1 | |
| SCHEMBL9701387 | 0.85 | CYP2C9 (0.47) | RAB9ACYP1A2LMNAGPR84HPGD | |
| SCHEMBL9701382 | 0.85 | SMN1; SMN2 (0.42) | RAB9ANPC1CYP1A2GAAMAPT | |
| SCHEMBL9700635 | 0.84 | GAA (0.39) | GAAHSD17B10MAPTLMNAMEN1 | |
| SCHEMBL9701582 | 0.84 | GCGR (0.39) | CYP1A2HSD17B10MAPTLMNAMEN1 | |
| SCHEMBL9700644 | 0.84 | PDE5A (0.38) | RAB9ANPC1CYP1A2GAAHSD17B10 | |
| SCHEMBL9525805 | 0.83 | CDC7 (0.36) | GAAMAPTMEN1KMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |