Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.32 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700651 | 0.93 | MAPT (0.35) | PDE3BPDE3AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL9700689 | 0.88 | RAB9A (0.33) | HSD17B10KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9528770 | 0.83 | KDM4E (0.48) | PDE3BPDE3AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL9700635 | 0.82 | GAA (0.39) | HSD17B10KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9526113 | 0.79 | MAPT (0.41) | KDM4EALDH1A1GAACYP2C9CYP1A2 | |
| SCHEMBL9701474 | 0.78 | CYP1A2 (0.41) | HSD17B10KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9701387 | 0.78 | CYP2C9 (0.47) | HPGDCYP2C9MOGAT2CYP1A2CYP2D6 | |
| SCHEMBL9701382 | 0.78 | SMN1; SMN2 (0.42) | KDM4EALDH1A1GAACYP2C9CYP1A2 | |
| SCHEMBL9529353 | 0.76 | CYP2C9 (0.34) | HSD17B10KDM4EALDH1A1CYP2C9MOGAT2 | |
| SCHEMBL9700666 | 0.75 | ALDH1A1 (0.53) | KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |