Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 8/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701474 | 0.95 | CYP1A2 (0.41) | CYP2C9CYP2C19CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL9701382 | 0.88 | SMN1; SMN2 (0.42) | CYP2C9CYP2C19CYP2D6CYP1A2CYP19A1 | |
| SCHEMBL9700689 | 0.85 | RAB9A (0.33) | CYP1A2GPR84XDHLMNAHPGD | |
| SCHEMBL9526113 | 0.82 | MAPT (0.41) | CYP2C9CYP2C19CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL9701582 | 0.81 | GCGR (0.39) | CYP2C9CYP1A2LMNAHPGDSMN1; SMN2 | |
| SCHEMBL9700644 | 0.80 | PDE5A (0.38) | CYP1A2LMNAHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9700651 | 0.80 | MAPT (0.35) | CYP2C9XDHLMNAHPGDRAB9A | |
| SCHEMBL9526401 | 0.80 | PTPN1 (0.36) | CYP2C9LMNASMN1; SMN2MOGAT2 | |
| SCHEMBL18778799 | 0.80 | MOGAT2 (0.57) | CYP2C9CYP2C19CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL6954855 | 0.79 | CYP2D6 (0.56) | CYP2C9CYP2C19CYP2D6CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |