Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701387 | 0.95 | CYP2C9 (0.47) | CYP1A2CYP2C9CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL9700689 | 0.90 | RAB9A (0.33) | CYP1A2RAB9ANPC1TP53HSD17B10 | |
| SCHEMBL9526113 | 0.87 | MAPT (0.41) | CYP1A2CYP2C9CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL9701582 | 0.85 | GCGR (0.39) | CYP1A2CYP2C9HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL9700644 | 0.84 | PDE5A (0.38) | CYP1A2RAB9ANPC1HSD17B10GAA | |
| SCHEMBL9525805 | 0.84 | CDC7 (0.36) | CYP2C9GAAMAPTALOX12KDM4E | |
| SCHEMBL9701382 | 0.84 | SMN1; SMN2 (0.42) | CYP1A2CYP2C9CYP2D6CYP19A1CYP2C19 | |
| SCHEMBL9524898 | 0.83 | PDE4A (0.37) | NPC1HSD17B10MAPTHPGDALDH1A1 | |
| SCHEMBL7644729 | 0.81 | PDE5A (0.47) | CYP1A2HSD17B10MAPTSMN1; SMN2HPGD | |
| SCHEMBL9701433 | 0.80 | PDE5A (0.33) | CYP1A2MAPTHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |