Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | GLP1R | P43220 | 6/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 3/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699664 | 0.78 | MMP1 (0.41) | MMP1MMP2MMP3GLP1RERBB2 | |
| SCHEMBL9700727 | 0.78 | PIK3CG (0.46) | ERBB2DYRK1A | |
| SCHEMBL30932231 | 0.78 | PIK3CG (0.46) | ERBB2DYRK1A | |
| SCHEMBL4177978 | 0.75 | ERBB2 (0.61) | MMP2ERBB2NQO2GAA | |
| SCHEMBL9699572 | 0.75 | ERBB2 (0.39) | ERBB2HTT | |
| SCHEMBL12124147 | 0.74 | MAPK13 (0.53) | MMP1MMP2MMP3GLP1RMAPK13 | |
| SCHEMBL7691783 | 0.73 | NQO2 (0.54) | ERBB2NQO2GAA | |
| SCHEMBL19470934 | 0.71 | NQO2 (0.52) | ERBB2NQO2GAA | |
| SCHEMBL6304069 | 0.71 | GLP1R (0.40) | MMP1MMP2MMP3GLP1RMAPK13 | |
| SCHEMBL1258596 | 0.70 | MMP1 (0.50) | MMP1MMP2MMP3GLP1RMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014740-A1 | QUINOXALINE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-03 | — | — | WO | disclosed |
| US-5118675-A | Therapy for central nervous system disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |