SCHEMBL97008

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL98414	0.78	LTA4H (0.46)	LTA4HTSHRKMT2AALDH1A1CYP1A2
	SCHEMBL9780873	0.77	LTA4H (0.55)	LTA4HTSHRKMT2AKDM4EGLA
	SCHEMBL10756887	0.76	MAOB (0.48)	LTA4HTSHRKMT2AKDM4EGLA
	SCHEMBL2096407	0.75	TTR (0.41)	LTA4HTSHRKMT2AKDM4EGLA
	SCHEMBL9273369	0.75	TSHR (0.52)	LTA4HTSHRKMT2AKDM4EGLA
	SCHEMBL4603157	0.75	LTA4H (0.60)	LTA4HTSHRKMT2AMAPTALDH1A1
	SCHEMBL9279528	0.74	LTA4H (0.52)	LTA4HTSHRKMT2AMAPTALDH1A1
	SCHEMBL28641946	0.74	TTR (0.60)	KMT2AKDM4EALDH1A1HPGDLMNA
	SCHEMBL22210568	0.74	LOXL2 (0.49)	LTA4HTSHRCYP1A2CYP3A4CYP2C9
	SCHEMBL10543494	0.74	LTA4H (0.41)	LTA4HTSHRKMT2ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.