SCHEMBL22210568

SCHEMBL22210568

NCc1cc(Oc2ccccc2)c(Oc2ccccc2)c(Oc2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 5/20 0.49
LOX P28300 2/20 0.47
DPP4 P27487 1/20 0.47
HRH1 P35367 1/20 0.46
ST14 Q9Y5Y6 1/20 0.44
TTR P02766 2/20 0.44
RHEB Q15382 1/20 0.41
LTA4H P09960 2/20 0.41
TSHR P16473 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
PLA2G2A P14555 1/20 0.40
KDM1A O60341 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15345331 0.79 LOXL2 (0.44) LOXL2LOXDPP4HRH1ST14
SCHEMBL2096411 0.78 TTR (0.49) TTRLTA4HTSHR
SCHEMBL2096407 0.78 TTR (0.41) HRH1TTRLTA4HTSHRCYP1A2
SCHEMBL920863 0.77 LOXL2 (0.53) LOXL2LOXDPP4HRH1ST14
SCHEMBL17241842 0.77 DPP4 (0.56) LOXL2LOXDPP4HRH1ST14
SCHEMBL97008 0.74 LTA4H (0.46) HRH1TTRLTA4HTSHRCYP1A2
SCHEMBL30851410 0.73 DPP4 (0.56) LOXL2LOXDPP4TTRCYP1A2
SCHEMBL921313 0.73 ROCK2 (0.50) LOXL2LOXDPP4HRH1ST14
SCHEMBL16945359 0.73 LOXL2 (0.49) LOXL2LOXDPP4HRH1ST14
SCHEMBL121432 0.73 ST14 (0.71) LOXL2DPP4ST14LTA4HTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10711033-B2 Branched chain-containing aromatic compound AJINOMOTO CO., INC. (JP) 2020-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711033-B2 Branched chain-containing aromatic compound VIP, IAPP, BCAT1 LOXL2 3217/4885LOX 2870/4885DPP4 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.