Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701583 | 0.80 | KDM4E (0.47) | KDM4ENPSR1ALDH1A1MAPK1MAPT | |
| SCHEMBL9701989 | 0.66 | CHRM2 (0.39) | KDM4ELMNAALOX5CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL9702735 | 0.65 | CHRM2 (0.38) | KDM4ELMNAALOX5CHRM2CHRM4 | |
| SCHEMBL11450020 | 0.62 | CYP3A4 (0.47) | L3MBTL1ALDH1A1MAPK1MAPTMEN1 | |
| SCHEMBL6780635 | 0.61 | LMNA (0.39) | KDM4ELMNASMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL4206097 | 0.61 | MMP8 (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL6204523 | 0.61 | MEN1 (0.49) | ALOX5SMN1; SMN2L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL23218354 | 0.60 | LMNA (0.47) | KDM4ELMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL10410232 | 0.60 | ESR1 (0.46) | LMNASMN1; SMN2ALDH1A1MAPK1CHRM1 | |
| SCHEMBL1767974 | 0.59 | LMNA (0.47) | KDM4ELMNASMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014465-A1 | USE OF ANNULATED TETRAHYDROPYRIDINACETIC ACID DERIVATES FOR TREATING NEUROLOGICAL DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1992-09-03 | — | — | WO | disclosed |