Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9702735 | 0.99 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9700862 | 0.83 | ADRB2 (0.37) | LMNAPRCPECE1 | |
| SCHEMBL9700852 | 0.80 | KMT2A (0.48) | KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL9703241 | 0.79 | KMT2A (0.48) | KMT2A | |
| SCHEMBL9702719 | 0.69 | MAOA (0.47) | KMT2ALMNA | |
| SCHEMBL6780635 | 0.67 | LMNA (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9700833 | 0.66 | KDM4E (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL3756009 | 0.65 | ESR1 (0.34) | ALOX5PPARGPPARAPTGES | |
| SCHEMBL3763814 | 0.65 | MAPKAPK2 (0.35) | KMT2AALOX5PPARGPPARAPTGES | |
| SCHEMBL19398219 | 0.62 | KMT2A (0.39) | KMT2APPARACA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014465-A1 | USE OF ANNULATED TETRAHYDROPYRIDINACETIC ACID DERIVATES FOR TREATING NEUROLOGICAL DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1992-09-03 | — | — | WO | disclosed |
| EP-0358957-A1 | Fused tetrahydropyridineacetic acid derivatives, process for their preparation, and use of such compounds for the cardioprotection | BOEHRINGER INGELHEIM KG (DE) | 1990-03-21 | — | — | EP | disclosed |