Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MB | P02144 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 3/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436140 | 0.72 | HTR5A (0.44) | KDM4EALDH1A1TYMSCYP1A2HPGD | |
| SCHEMBL3605239 | 0.66 | MAOA (0.37) | KDM4EALDH1A1TYMSCYP1A2HPGD | |
| SCHEMBL3605242 | 0.66 | MAOA (0.37) | KDM4EALDH1A1TYMSCYP1A2HPGD | |
| SCHEMBL14805480 | 0.66 | ALDH1A1 (0.39) | KDM4EALDH1A1TYMSCYP1A2HPGD | |
| SCHEMBL24711772 | 0.62 | HTR1A (0.33) | KDM4EALDH1A1TYMSCYP1A2HPGD | |
| SCHEMBL12030669 | 0.61 | GAA (0.59) | KDM4EALDH1A1GAAPOLB | |
| SCHEMBL464780 | 0.58 | AHR (0.50) | KDM4EALDH1A1TYMSCYP1A2HPGD | |
| SCHEMBL20881863 | 0.58 | MAPT (0.47) | KDM4EALDH1A1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL9700774 | 0.57 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL10959840 | 0.57 | AHR (0.45) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510235-A1 | Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same | DONG-A PHARM. CO., LTD. (KR) | 1992-10-28 | — | — | EP | disclosed |