Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.51 |
| ▸ | NPC1 | O15118 | 9/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702278 | 0.98 | RAB9A (0.53) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10797169 | 0.83 | RAB9A (0.64) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL17750392 | 0.82 | RAB9A (0.60) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9701997 | 0.82 | RAB9A (0.60) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL23458469 | 0.81 | RAB9A (0.49) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10803663 | 0.78 | APP (0.51) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9298339 | 0.74 | ALDH1A1 (0.73) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL15473569 | 0.73 | NPC1 (0.57) | RAB9ANPC1ALDH1A3KDM4EALDH1A1 | |
| SCHEMBL9702800 | 0.72 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL18341919 | 0.70 | RAB9A (0.43) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012154-A1 | IMIDAZOTRIAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-23 | — | — | WO | disclosed |