Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | GLA | P06280 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 11/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10797169 | 0.84 | RAB9A (0.64) | RAB9AALDH1A1KDM4EHPGDGAA | |
| SCHEMBL9702278 | 0.83 | RAB9A (0.53) | RAB9AALDH1A1KDM4EHPGDGAA | |
| SCHEMBL17750392 | 0.83 | RAB9A (0.60) | RAB9AALDH1A1KDM4EHPGDGAA | |
| SCHEMBL23458469 | 0.83 | RAB9A (0.49) | RAB9AALDH1A1KDM4EHPGDGAA | |
| SCHEMBL9700913 | 0.82 | RAB9A (0.51) | RAB9AALDH1A1KDM4EHPGDGAA | |
| SCHEMBL10803663 | 0.80 | APP (0.51) | RAB9AALDH1A1KDM4EGAANPC1 | |
| SCHEMBL1692157 | 0.75 | ALDH1A1 (1.00) | RAB9AALDH1A1KDM4EHPGDGAA | |
| SCHEMBL9702800 | 0.70 | KDM4E (0.62) | ALDH1A1KDM4EHPGDTP53LMNA | |
| SCHEMBL23486250 | 0.69 | RAB9A (0.40) | RAB9AALDH1A1KDM4EHPGDGAA | |
| SCHEMBL17750400 | 0.69 | KDM4E (0.84) | RAB9AALDH1A1KDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012154-A1 | IMIDAZOTRIAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-23 | — | — | WO | disclosed |