Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | FGB | P02675 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701297 | 0.87 | MEN1 (0.54) | POLBMEN1KMT2AFGBALDH1A1 | |
| SCHEMBL29515337 | 0.78 | ALDH1A1 (0.45) | POLBMEN1KMT2AFGBALDH1A1 | |
| SCHEMBL24188895 | 0.78 | ALDH1A1 (0.45) | POLBMEN1KMT2AFGBALDH1A1 | |
| Succinic Acid SCHEMBL11703500 | 0.76 | POLB (0.46) | POLBMEN1KMT2AFGBKIF11 | |
| SCHEMBL11605828 | 0.74 | ALDH1A1 (0.49) | ALDH1A1CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL12276383 | 0.73 | KDM4E (0.55) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5143206 | 0.73 | ALDH1A1 (0.49) | POLBMEN1KMT2AFGBALDH1A1 | |
| SCHEMBL29514990 | 0.73 | ALDH1A1 (0.49) | POLBMEN1KMT2AFGBALDH1A1 | |
| SCHEMBL10745713 | 0.71 | FKBP1A (0.54) | MEN1KMT2AALDH1A1MAPTHSD17B10 | |
| SCHEMBL29102676 | 0.71 | ALDH1A1 (0.51) | POLBMEN1KMT2AFGBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063225-A | Antiarrhythmia | ROUSSEL UCLAF (FR) | 1991-11-05 | — | — | US | disclosed |