Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 4/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701346 | 0.81 | KDM4E (0.64) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9701544 | 0.80 | KDM4E (0.70) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9701560 | 0.78 | KDM4E (0.59) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9700710 | 0.76 | KDM4E (0.64) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9700707 | 0.76 | KDM4E (0.71) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9530230 | 0.76 | MDM2 (0.41) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9700772 | 0.74 | XDH (0.35) | KDM4EALDH1A1GAAHPGDLMNA | |
| SCHEMBL11740127 | 0.74 | KDM4E (0.57) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL11736261 | 0.73 | KDM4E (0.60) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9526090 | 0.73 | KDM4E (0.74) | KDM4EALDH1A1GAAGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |