Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701567 | 0.77 | MDM2 (0.50) | MDM2KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL9702576 | 0.77 | KDM4E (0.38) | MDM2KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL7375974 | 0.73 | KDM4E (0.48) | MDM2KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL7256598 | 0.72 | PIM1 (0.58) | MDM2KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL1201107 | 0.69 | KDM4E (0.53) | MDM2KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL9530249 | 0.69 | KDM4E (0.38) | MDM2KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL1463691 | 0.68 | CYP19A1 (0.36) | KDM4EALDH1A1CYP2C19 | |
| SCHEMBL11937881 | 0.68 | CYP3A4 (0.38) | KDM4EALDH1A1LMNATSHRCYP2C19 | |
| SCHEMBL4474609 | 0.67 | MDM2 (0.62) | MDM2KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL9700418 | 0.67 | CYP2A6 (0.34) | KDM4EALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |