Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | BIRC5 | O15392 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4474609 | 0.79 | MDM2 (0.62) | MDM2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9701360 | 0.77 | MDM2 (0.45) | MDM2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9701575 | 0.76 | MDM2 (0.59) | MDM2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL8382823 | 0.76 | ESR2 (0.47) | KDM4EALDH1A1GAAHPGDGALR3 | |
| SCHEMBL19411747 | 0.72 | MDM2 (0.49) | MDM2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9700691 | 0.71 | PTGS2 (0.35) | KDM4EALDH1A1L3MBTL1ATMKMT2A | |
| SCHEMBL7256598 | 0.71 | PIM1 (0.58) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL9702576 | 0.70 | KDM4E (0.38) | MDM2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9526258 | 0.69 | KDM4E (0.64) | MDM2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9526262 | 0.69 | ALDH1A1 (0.67) | MDM2KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |