Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530249 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9701360 | 0.77 | MDM2 (0.45) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9700783 | 0.72 | — | — | |
| SCHEMBL1258908 | 0.72 | CRHBP (0.49) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL20869442 | 0.71 | TYR (0.39) | KDM4EALDH1A1GAAHPGDPDE3B | |
| SCHEMBL9701567 | 0.70 | MDM2 (0.50) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9432027 | 0.68 | PDE3B (0.48) | KDM4EALDH1A1GAAHPGDPDE3B | |
| SCHEMBL9528029 | 0.68 | KDM4E (0.52) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL2305264 | 0.67 | HSD17B10 (0.37) | KDM4EALDH1A1L3MBTL1HPGDHTT | |
| SCHEMBL21652406 | 0.66 | LIPG (0.41) | KDM4EALDH1A1HPGDHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |