Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528029 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1L3MBTL1GLAGAA | |
| SCHEMBL5097681 | 0.91 | ALDH1A1 (0.49) | KDM4EALDH1A1L3MBTL1GLAGAA | |
| SCHEMBL9703127 | 0.88 | ALDH1A1 (0.57) | KDM4EALDH1A1L3MBTL1GLAGAA | |
| SCHEMBL9700707 | 0.85 | KDM4E (0.71) | KDM4EALDH1A1L3MBTL1GLAGAA | |
| SCHEMBL9701460 | 0.83 | ALDH1A1 (0.52) | KDM4EALDH1A1L3MBTL1GLAGAA | |
| SCHEMBL7260450 | 0.81 | KDM4E (0.70) | KDM4EALDH1A1L3MBTL1GLAGAA | |
| SCHEMBL9526882 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1L3MBTL1GLAGAA | |
| SCHEMBL9702581 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1L3MBTL1GLAGAA | |
| SCHEMBL9701544 | 0.81 | KDM4E (0.70) | KDM4EALDH1A1L3MBTL1GLAGAA | |
| SCHEMBL9526844 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1L3MBTL1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |