Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647544 | 0.93 | ALDH1A1 (0.54) | ALDH1A1KDM4EL3MBTL1GLAGAA | |
| SCHEMBL9526882 | 0.91 | ALDH1A1 (0.44) | ALDH1A1KDM4EL3MBTL1GLAGAA | |
| SCHEMBL7576593 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KDM4EL3MBTL1GLAGAA | |
| SCHEMBL7376004 | 0.87 | PDE5A (0.50) | ALDH1A1KDM4EL3MBTL1GLAGAA | |
| SCHEMBL7650243 | 0.87 | ALDH1A1 (0.41) | ALDH1A1KDM4EL3MBTL1GLAGAA | |
| SCHEMBL9525981 | 0.86 | KDM4E (0.48) | ALDH1A1KDM4EL3MBTL1GLAGAA | |
| SCHEMBL7648674 | 0.85 | AR (0.40) | ALDH1A1KDM4EL3MBTL1GLAGAA | |
| SCHEMBL7646410 | 0.84 | ALDH1A1 (0.58) | ALDH1A1XDHHPGD | |
| SCHEMBL7644788 | 0.84 | PDE5A (0.45) | ALDH1A1KDM4EL3MBTL1GLAGAA | |
| SCHEMBL7646373 | 0.84 | L3MBTL1 (0.54) | ALDH1A1KDM4EL3MBTL1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |