Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526844 | 0.94 | KDM4E (0.55) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9701461 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9701458 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9701620 | 0.84 | KDM4E (0.57) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9701393 | 0.83 | KDM4E (0.52) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9703127 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9700707 | 0.81 | KDM4E (0.71) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL7576593 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9702581 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9701530 | 0.80 | KDM4E (0.65) | ALDH1A1KDM4EGLAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |