Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22410717 | 0.78 | PDE10A (0.51) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL661077 | 0.76 | CYP3A4 (0.48) | ALDH1A1HPGDMAPTCYP3A4KMT2A | |
| SCHEMBL29589760 | 0.76 | CYP3A4 (0.48) | ALDH1A1HPGDMAPTCYP3A4KMT2A | |
| SCHEMBL2590289 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL48303 | 0.72 | CYP3A4 (0.45) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL9362794 | 0.68 | NPC1 (0.46) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL5658262 | 0.68 | ALDH1A1 (0.49) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL1169526 | 0.67 | CYP3A4 (0.43) | ALDH1A1HPGDGLAMAPTCYP3A4 | |
| SCHEMBL2865289 | 0.67 | SMN1; SMN2 (0.51) | ALDH1A1HPGDGLAMAPTKMT2A | |
| SCHEMBL15431 | 0.66 | CYP3A4 (0.64) | ALDH1A1HPGDMAPTCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118499-A | Quinoline polymers, their chelates and process of preparation and use | THEODOROPULOS SPYROS (US) | 1992-06-02 | — | — | US | disclosed |