Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526844 | 0.91 | KDM4E (0.55) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9701530 | 0.90 | KDM4E (0.65) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9701927 | 0.88 | KDM4E (0.55) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9524533 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9700696 | 0.86 | KDM4E (0.53) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9701460 | 0.84 | ALDH1A1 (0.52) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL11174883 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9701626 | 0.82 | ALDH1A1 (0.56) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9701665 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9701913 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1GAAGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |