Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701271 | 0.77 | PGR (0.32) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL9702705 | 0.77 | TP53 (0.30) | — | |
| SCHEMBL13930531 | 0.76 | ALDH1A1 (0.38) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL9701587 | 0.75 | — | — | |
| SCHEMBL27472778 | 0.71 | TSHR (0.33) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL18086541 | 0.71 | TP53 (0.33) | — | |
| SCHEMBL3515611 | 0.67 | TP53 (0.36) | — | |
| SCHEMBL9700384 | 0.67 | — | — | |
| SCHEMBL437673 | 0.66 | FDPS (0.36) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL209469 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132454-A | Antihypoxic agents | MEIJI SEIKA KAISHA, LTD. (JP) | 1992-07-21 | — | — | US | disclosed |
| US-5066677-A | Antihypoxic agents, treatment of disorders resulting from reduced oxygen supply to brain | MEIJI SEIKA KAISHA, LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0387074-A2 | Novel oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain | MEIJI SEIKA KAISHA LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |