Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | LAP3 | P28838 | 2/20 | 0.35 |
| ▸ | KYNU | Q16719 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700628 | 0.89 | LAP3 (0.36) | LTA4HLAP3MEN1HTTKMT2A | |
| SCHEMBL9701731 | 0.72 | LTA4H (0.38) | LTA4HLAP3SLC15A1 | |
| SCHEMBL9700735 | 0.69 | CYP1A2 (0.48) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL27705770 | 0.66 | ALDH1A1 (0.53) | LTA4HLAP3SLC15A1ALDH1A1MEN1 | |
| SCHEMBL21189194 | 0.65 | ALDH1A1 (0.45) | LTA4HLAP3KYNUSLC15A1ALDH1A1 | |
| SCHEMBL21189144 | 0.65 | ALDH1A1 (0.45) | LTA4HLAP3KYNUSLC15A1ALDH1A1 | |
| SCHEMBL17878731 | 0.64 | ALDH1A1 (0.55) | LTA4HLAP3SLC15A1ALDH1A1MEN1 | |
| SCHEMBL13302682 | 0.64 | ALDH1A1 (0.55) | LTA4HLAP3SLC15A1ALDH1A1MEN1 | |
| SCHEMBL12053128 | 0.64 | ALDH1A1 (0.55) | LTA4HLAP3SLC15A1ALDH1A1MEN1 | |
| SCHEMBL8232952 | 0.64 | ALDH1A1 (0.55) | LTA4HLAP3SLC15A1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014740-A1 | QUINOXALINE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-03 | — | — | WO | disclosed |
| US-5118675-A | Therapy for central nervous system disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |