Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | DPYD | Q12882 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526090 | 0.84 | KDM4E (0.74) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9700707 | 0.82 | KDM4E (0.71) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9701544 | 0.81 | KDM4E (0.70) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9525492 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9526447 | 0.80 | GAA (1.00) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL4474609 | 0.77 | MDM2 (0.62) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9700710 | 0.77 | KDM4E (0.64) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9702632 | 0.77 | XDH (0.48) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9702637 | 0.77 | XDH (0.48) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9700724 | 0.76 | KDM4E (0.66) | KDM4EALDH1A1GLAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |