Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 15/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 14/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | PDE1A | P54750 | 1/20 | 0.48 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.48 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.48 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701530 | 0.86 | KDM4E (0.65) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9700696 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9701620 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL8206942 | 0.78 | PDE5A (0.57) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL9701665 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9701927 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9526844 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9524533 | 0.76 | KDM4E (0.54) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL11174883 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9700749 | 0.75 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |