Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 17/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 17/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524898 | 0.80 | PDE4A (0.37) | PDE4APDE4BPDE4D | |
| SCHEMBL9700632 | 0.79 | PDE4B (0.35) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9524493 | 0.79 | XDH (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9526095 | 0.77 | ALOX5 (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9526087 | 0.77 | ALOX5 (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9701913 | 0.75 | KDM4E (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9700635 | 0.74 | GAA (0.39) | — | |
| SCHEMBL9700666 | 0.73 | ALDH1A1 (0.53) | — | |
| SCHEMBL9525928 | 0.72 | CYP11B1 (0.33) | — | |
| SCHEMBL127547 | 0.71 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |