Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994981 | 0.90 | LTB4R (0.57) | LTB4RLTB4R2MAOBKDM4EALDH1A1 | |
| SCHEMBL9699613 | 0.83 | LTB4R (0.59) | LTB4RLTB4R2MAOBKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9701746 | 0.83 | GAA (0.43) | LTB4RLTB4R2MAOBALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9701722 | 0.83 | LTB4R (0.58) | LTB4RLTB4R2MAOBKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9700771 | 0.82 | THRA (0.41) | LTB4RLTB4R2MAOBMAPTLSS | |
| Hydrochloric Acid SCHEMBL9700974 | 0.81 | LTB4R (0.46) | LTB4RLTB4R2MAPTGAAHDAC8 | |
| Hydrochloric Acid SCHEMBL9701752 | 0.78 | LTB4R (0.39) | LTB4RLTB4R2ALDH1A1MAPTHDAC8 | |
| Hydrochloric Acid SCHEMBL9701749 | 0.76 | THRA (0.39) | LTB4RLTB4R2MAOBNPSR1MAPT | |
| SCHEMBL9700776 | 0.76 | LTB4R (0.37) | LTB4RLTB4R2GAALSSHDAC8 | |
| Hydrochloric Acid SCHEMBL9700781 | 0.75 | LTB4R (0.36) | LTB4RLTB4R2MAPTGAAGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518819-A2 | Amidino compounds, their manufacture and use as medicament | CIBA-GEIGY AG (CH) | 1992-12-16 | — | — | EP | disclosed |