Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588503 | 1.00 | CYP2C9 (0.35) | CYP2C9CYP2C19MAPK1LMNAPOLB | |
| SCHEMBL9588419 | 0.87 | F10 (0.33) | POLBALDH1A1MEN1KMT2A | |
| SCHEMBL9589012 | 0.85 | ALDH1A1 (0.36) | CYP2C9CYP2C19MAPK1LMNAPOLB | |
| SCHEMBL9701739 | 0.84 | ABCC9 (0.39) | CYP2C9CYP2C19LMNACYP1A2 | |
| SCHEMBL9589428 | 0.84 | ABCC9 (0.39) | CYP2C9CYP2C19LMNACYP1A2 | |
| SCHEMBL9588118 | 0.83 | PDK2 (0.38) | POLB | |
| SCHEMBL9587584 | 0.77 | ABCC9 (0.39) | CYP2C9CYP2C19LMNAPOLBALDH1A1 | |
| SCHEMBL9589616 | 0.76 | MAPK1 (0.36) | MAPK1LMNAPOLBALDH1A1TSHR | |
| SCHEMBL9702073 | 0.76 | TDP2 (0.34) | CYP2C9CYP2C19POLBALDH1A1TDP2 | |
| SCHEMBL9588737 | 0.76 | TDP2 (0.34) | CYP2C9CYP2C19POLBALDH1A1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489300-A2 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1992-06-10 | — | — | EP | disclosed |