Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588737 | 1.00 | TDP2 (0.34) | TDP2CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL9589012 | 0.85 | ALDH1A1 (0.36) | TDP2CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL9702026 | 0.76 | CYP2C9 (0.35) | TDP2CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL9588503 | 0.76 | CYP2C9 (0.35) | TDP2CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL9589616 | 0.75 | MAPK1 (0.36) | CYP1A2POLBALDH1A1TSHRCA1 | |
| SCHEMBL9733666 | 0.73 | ALDH1A1 (0.38) | POLBSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL9143340 | 0.72 | ABCC9 (0.45) | CYP1A2CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL9143344 | 0.72 | ABCC9 (0.45) | CYP1A2CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL9143349 | 0.72 | ABCC9 (0.45) | CYP1A2CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL9588271 | 0.71 | DRD2 (0.34) | ALDH1A1MEN1KMT2ANPSR1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489300-A2 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1992-06-10 | — | — | EP | disclosed |