Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MDH1 | P40925 | 1/20 | 0.39 |
| ▸ | MDH2 | P40926 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701922 | 0.80 | ESR1 (0.41) | SLC6A2SLC6A3 | |
| SCHEMBL9703429 | 0.79 | MAOB (0.49) | MAOBAOC3TAAR1 | |
| SCHEMBL9702766 | 0.79 | MAOB (0.44) | MAOB | |
| SCHEMBL9702021 | 0.78 | MAOB (0.50) | MAOBAOC3TAAR1 | |
| SCHEMBL9702170 | 0.78 | MAOB (0.38) | MAOBAOC3ALDH1A1 | |
| SCHEMBL12107925 | 0.73 | MAOB (0.59) | MAOBAOC3ALDH1A1PPARD | |
| SCHEMBL1294612 | 0.73 | MAOB (0.69) | MAOBAOC3ALDH1A1 | |
| SCHEMBL1294618 | 0.73 | MAOB (0.69) | MAOBAOC3ALDH1A1 | |
| SCHEMBL1294616 | 0.73 | MAOB (0.69) | MAOBAOC3ALDH1A1 | |
| SCHEMBL9701873 | 0.73 | MAOB (0.38) | MAOBAOC3ALDH1A1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |