Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AOC2 | O75106 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702170 | 0.84 | MAOB (0.38) | MAOBAOC3HPGDMAPTALDH1A1 | |
| SCHEMBL9703429 | 0.83 | MAOB (0.49) | MAOBAOC3MAPTLMNAGAA | |
| SCHEMBL9703334 | 0.80 | — | — | |
| SCHEMBL9701922 | 0.78 | ESR1 (0.41) | LMNA | |
| SCHEMBL9702766 | 0.76 | MAOB (0.44) | MAOBHPGDMAPTSMN1; SMN2 | |
| SCHEMBL9702021 | 0.76 | MAOB (0.50) | MAOBAOC3AOC2DAOMAOA | |
| SCHEMBL9702192 | 0.73 | MAOB (0.54) | MAOBAOC3ALDH1A1PPARD | |
| SCHEMBL11219413 | 0.71 | ALOX15 (0.55) | HPGDMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9703320 | 0.70 | AGXT (0.54) | HPGDALDH1A1LMNANPSR1 | |
| SCHEMBL9700886 | 0.70 | CA12 (0.47) | HPGDMAPTALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |