Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATF4 | P18848 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701922 | 0.84 | ESR1 (0.41) | PTGS2 | |
| SCHEMBL9703429 | 0.83 | MAOB (0.49) | MAOBMAPT | |
| SCHEMBL9702021 | 0.82 | MAOB (0.50) | MAOB | |
| SCHEMBL9702170 | 0.81 | MAOB (0.38) | MAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL9702192 | 0.79 | MAOB (0.54) | MAOB | |
| SCHEMBL9701873 | 0.76 | MAOB (0.38) | MAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL9703320 | 0.76 | AGXT (0.54) | POLBHPGDRAB9A | |
| SCHEMBL9701919 | 0.73 | MEN1 (0.43) | SMN1; SMN2POLBMAPTHPGDRAB9A | |
| SCHEMBL9702218 | 0.72 | APP (0.43) | — | |
| SCHEMBL10506665 | 0.71 | ATF4 (0.47) | SMN1; SMN2ATF4POLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |