Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | AOC2 | O75106 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701922 | 0.84 | ESR1 (0.41) | LTA4H | |
| SCHEMBL9702766 | 0.82 | MAOB (0.44) | MAOB | |
| SCHEMBL9703429 | 0.82 | MAOB (0.49) | MAOBTAAR1AOC3KMT2A | |
| SCHEMBL9702218 | 0.82 | APP (0.43) | TAAR1FFAR1 | |
| SCHEMBL9703320 | 0.82 | AGXT (0.54) | MEN1KMT2A | |
| SCHEMBL9702170 | 0.81 | MAOB (0.38) | MAOBAOC2MAOADAOAOC3 | |
| SCHEMBL9702192 | 0.78 | MAOB (0.54) | MAOBTAAR1AOC3 | |
| SCHEMBL9701919 | 0.76 | MEN1 (0.43) | MEN1KMT2A | |
| SCHEMBL9701657 | 0.76 | AOC2 (0.55) | MAOBAOC2MAOAALOX15MEN1 | |
| SCHEMBL9701873 | 0.76 | MAOB (0.38) | MAOBAOC2MAOADAOAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |