Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701922 | 0.84 | ESR1 (0.41) | LMNA | |
| SCHEMBL9701873 | 0.83 | MAOB (0.38) | MAOBAOC3GAALMNAMAPT | |
| SCHEMBL9702766 | 0.83 | MAOB (0.44) | MAOBMAPT | |
| SCHEMBL9702021 | 0.82 | MAOB (0.50) | MAOBAOC3TAAR1KMT2A | |
| SCHEMBL9700886 | 0.82 | CA12 (0.47) | TAAR1GAALMNAMAPTKMT2A | |
| SCHEMBL9702170 | 0.81 | MAOB (0.38) | MAOBAOC3GAALMNAMAPT | |
| SCHEMBL9701935 | 0.79 | TAAR1 (0.52) | MAOBTAAR1 | |
| SCHEMBL9702192 | 0.79 | MAOB (0.54) | MAOBAOC3TAAR1 | |
| SCHEMBL9702039 | 0.76 | SMN1; SMN2 (0.47) | TAAR1GAALMNAMAPTKMT2A | |
| SCHEMBL9703320 | 0.76 | AGXT (0.54) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |