Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700880 | 0.85 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDTSHRMAPT | |
| SCHEMBL16891415 | 0.80 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDTSHRMAPT | |
| SCHEMBL9701867 | 0.78 | CA2 (0.37) | KDM4EALDH1A1HPGDTSHRMAPT | |
| SCHEMBL9702172 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTSMN1; SMN2CA12 | |
| SCHEMBL9702758 | 0.72 | HDAC1 (0.38) | KDM4EHPGDTSHRMAPTHSD17B10 | |
| SCHEMBL5495294 | 0.72 | HPGD (0.46) | KDM4EALDH1A1HPGDTSHRMAPT | |
| SCHEMBL9014128 | 0.71 | CA1 (0.39) | KDM4EALDH1A1HPGDTSHRMAPT | |
| SCHEMBL29056070 | 0.70 | HPGD (0.35) | KDM4EALDH1A1HPGDTSHRMAPT | |
| SCHEMBL12812548 | 0.68 | KMT2A (0.50) | KDM4EALDH1A1HPGDTSHRMAPT | |
| SCHEMBL22791309 | 0.68 | KDM4E (0.46) | KDM4EALDH1A1HPGDTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |