Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702223 | 0.85 | KDM4E (0.42) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| SCHEMBL9701867 | 0.79 | CA2 (0.37) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| SCHEMBL9702172 | 0.74 | ALDH1A1 (0.46) | ALDH1A1LMNACA1CA2MAPT | |
| SCHEMBL16891415 | 0.73 | ALDH1A1 (0.39) | ALDH1A1HPGDHSD17B10ALOX15CA1 | |
| SCHEMBL14645922 | 0.71 | ALOX5 (0.50) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| SCHEMBL9703351 | 0.70 | CA12 (0.42) | ALDH1A1LMNACA1CA2ALOX5 | |
| SCHEMBL11110834 | 0.68 | ALDH1A1 (0.41) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| SCHEMBL9701892 | 0.68 | TAAR1 (0.44) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| SCHEMBL9702052 | 0.67 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10LMNAALOX15 | |
| SCHEMBL9702814 | 0.66 | LMNA (0.39) | ALDH1A1HPGDHSD17B10LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |