Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701190 | 0.81 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL9436772 | 0.76 | CHRNB2 (0.34) | RAB9ATAS1R3TAS1R1TAS1R2PDE4A | |
| SCHEMBL9535908 | 0.76 | CHRNB2 (0.34) | RAB9ATAS1R3TAS1R1TAS1R2PDE4A | |
| SCHEMBL9701430 | 0.71 | CA1 (0.33) | RAB9ATAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL9700197 | 0.69 | MAOB (0.32) | TAS1R3TAS1R1TAS1R2KMT2AKDM4E | |
| SCHEMBL9701418 | 0.68 | CHRNB2 (0.40) | RAB9AKMT2AKDM4EALDH1A1CYP3A4 | |
| SCHEMBL19582451 | 0.67 | MAPT (0.41) | RAB9AKMT2ALMNAALDH1A1SIGMAR1 | |
| SCHEMBL9702535 | 0.67 | MAPT (0.35) | RAB9AKDM4ELMNAALDH1A1CYP3A4 | |
| SCHEMBL7902260 | 0.65 | CYP1A2 (0.35) | RAB9AKMT2AERN1KDM4EALDH1A1 | |
| SCHEMBL7902256 | 0.65 | CYP1A2 (0.35) | RAB9AKMT2AERN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013860-A1 | NEW 4,5,6,7-TETRAHYDRO-IMIDAZO-[4,5,lJK][1,4]-BENZODIAZEPINE-2-(1H)-THIONES, A METHOD OF PREPARING THEM AS WELL AS DRUGS CONTAINING THEM, AND INTERMEDIATES FOR THE PREPARATION OF THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-20 | — | — | WO | disclosed |